MSF in Khayelitsha has developed a programme that supports people with HIV to receive COVID-19 vaccination jabs on the same day as their routine clinic visit. Since early December 2021, the programme has supported jabs for more than 3000 at-risk individuals in 3 clinics. In parallel, MSF teams in Khayelitsha have been taking vaccination into the community. Our approach includes the running of pop-up vaccine sites in busy community locales, supported by dazzling mural artworks that speak directly to hard-to-reach groups to encourage them to get vaccinated, like males and young people.