In Africa, Zambia is one of the country's how is severely hit by the HIV/AIDS epidemic; 22 percent of the population is HIV-positive. Nchengele district in the province of Luapula is one of the area's hardest hit in Zambia. MSF-Holland has been working here since 2001. The activities include counselling and testing, providing information and education, prevention of transmission from mother to child. Original the intervention started on a home-based care (HBC) basis. Since then, an extensive collaboration with 6 health centres in the district has been set up. Together, they cover more then half of the population in the district. Most of the HIV/AIDS care takes place in the health centres while the home-based care component focuses on the patients who are too weak to come to the health-centres.